The Spectrum of Surgical Remediation of Transoral Incisionless Fundoplication-Related Failures

AIM: To evaluate outcomes of surgical remediation for symptomatic or anatomic failure after a transoral incisionless fundoplication (TIF). METHODS: This retrospective study was performed on 11 patients who underwent a remedial operation following TIF failure between June 2011 and September 2016 at the Mayo Clinic in Florida for persistent foregut symptoms. Upper gastrointestinal workup characterized… Read more »

Transoral Incisionless Fundoplication: Is It as Safe and Efficacious as a Nissen or Toupet Fundoplication?

Abstract: Transoral incisionless fundoplication (TIF) was U.S. Food and Drug Administration-approved in 2007 to treat gastroesophageal reflux disease (GERD), but comparative data are lacking. This study was undertaken to compare outcomes for patients with GERD undergoing TIF versus laparoscopic Nissen or Toupet fundoplications. We undertook a case-controlled study of three cohorts of 20 patients undergoing TIF or laparoscopic Nissen… Read more »

Total vs Partial Fundoplication in the Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis

OBJECTIVE: To perform a meta-analysis of randomized trials comparing partial fundoplication (PF) with total (Nissen) fundoplication (TF) for gastroesophageal reflux disease in terms of morbidity, efficacy, and long-term symptomatology. DATA SOURCES: A structured Medline search for published studies. STUDY SELECTION: The available literature from 1975 until June 2007 was searched using the Medical Subject Headings… Read more »

Endoscopic appraisal of the gastroesophageal valve after antireflux surgery

OBJECTIVES: Little consensus exists regarding the endoscopic assessment of the esophagogastric junction after antireflux surgery. The purpose of this report is to characterize the gastroesophageal valve appearance unique to each type of antireflux procedure and to introduce an endoscopic lexicon by which to describe this anatomic region. METHODS: Endoscopic images were obtained from patients who… Read more »

The Treatment of Hiatal Hernia and Esophageal Reflux by Fundoplication

Nissen, R. (1964). The treatment of hiatal hernia and esophageal reflux by fundoplication (chapter 30). In L.M. Nyhus & H.N. Harkins (Eds), Hernia (1st ed., pp.488-96). Philadelphia, PA: Lippincott. After searches in, and we were unable to locate a digital copy of this book chapter. The following material may be protected by… Read more »