Cigarette smoking is thought to adversely affect gastroesophageal reflux. Eight male patients with endoscopic evidence of gastroesophageal reflux had 24-h esophageal pH monitoring while smoking at least 20 cigarettes. This was repeated while abstaining from smoking the following day. In the initial study period, 28.3% of the reflux time occurred within 20 min of smoking… Read more »
Responses of feline gastroesophageal junction to changes in abdominal pressure
The responses of the lower esophageal sphincter (LES), stomach, and diaphragm and their contribution to changes in the high-pressure zone (HPZ) at the gastroesophageal junction were determined during extrinsic abdominal compression or intragastric balloon distension in anesthetized cats. Abdominal compression consistently induced an increase in intraluminal end-expiratory LES and gastric pressure (P less than 0.01).… Read more »
Role of the diaphragm in the genesis of lower esophageal sphincter pressure in the cat
To determine the role of the diaphragm in the genesis of the high-pressure zone at the lower esophageal sphincter (LES) we studied the effect of diaphragmatic contraction on lower esophageal sphincter pressure in 10 anesthetized adult cats. Despite anchoring the pressure recording assembly within the LES to prevent axial movement of the sphincter during respiration… Read more »
Evaluation of elevation of the head of the bed, bethanechol, and antacid foam tablets on gastroesophageal reflux
To ascertain how elevation of the head of the bed, bethanechol, and antacid foam tablets affect gastroesophageal reflux, we used prolonged intraesophageal pH monitoring in 55 symptomatic patients. Acid exposure was separated into reflux frequency and esophageal acid clearance time and recorded during the day in the upright posture and recumbent at night. Values before… Read more »
The Treatment of Hiatal Hernia and Esophageal Reflux by Fundoplication
Nissen, R. (1964). The treatment of hiatal hernia and esophageal reflux by fundoplication (chapter 30). In L.M. Nyhus & H.N. Harkins (Eds), Hernia (1st ed., pp.488-96). Philadelphia, PA: Lippincott. After searches in PubMed.gov, Amazon.com and AbeBooks.com we were unable to locate a digital copy of this book chapter. The following material may be protected by… Read more »
A valve mechanism to prevent gastroesophageal reflux and esophagitis
Adler RH, Firme CN, Lanigan JM. A valve mechanism to prevent gastroesophageal reflux and esophagitis. Surgery. 1958;44:63-75. After searches in PubMed.gov, Amazon.com and AbeBooks.com we were unable to locate a digital copy of this peer-reviewed clinical publication. This material may be protected by copyright law. It is our intent to honor Drs Richard H Adler,… Read more »